Using the shot

Fifty 410 vs Noom Med

$133/mo against $149/mo for tirzepatide. Which is worth it, and for whom.

Illustration of two objects on a balance scale

Updated 2026-09-18

How we are paid: one company on this page — Coreage Rx — pays us a commission if you sign up through our link. It does not buy a better score, a higher position, or the removal of a single criticism. Our rating method and full disclosure are both public.


Both sell tirzepatide. Fifty 410 costs $133 a month and Noom Med costs $149, a difference of $16 a month or about $192 a year. The other differences matter more than the money if this is your first course.

Fifty 410 is prepaid blocks with no subscription. Noom Med is behaviour change alongside medication. They are not aimed at the same person, and the cheaper one is not automatically the right answer — particularly if this is your first course and you expect a slow titration.

What this means for your titration. Both price the same way as your dose climbs, so the gap between them stays constant the whole way up the ladder.

Side by side

Fifty 410Noom Med
Advertised from$133$149
Membership on topNoneNone
True monthly cost$133$149
Roughly, per year$1,596$1,788
Price includes medicationYesYes, at microdoses
Names its pharmacyNot publishedNot published
Our score4.2 / 53.5 / 5

Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.

The differences that affect treatment

They differ on 2 of the 7 things we track, and behave the same on the other 5. The differences are what the price gap is actually buying.

Fifty 410Noom
Month-to-month without prepaying a blockNoYes
Medication included in the monthly priceYesNo

What each programme publishes: Fifty 410

  • Compounded tirzepatide starter protocol at $133/month, sold as a $399 three-month block.
  • High-dose tirzepatide protocol at $183/month, sold as a $549 three-month block.
  • No membership, no subscription and no recurring charges — you buy a block outright.
  • Provider consultation and free 1-2 day shipping included in the price.
  • States it is a telehealth platform that does not compound or distribute medication itself, and that preparations come from FDA-registered 503A pharmacies.
  • Publishes unusually detailed information on 503A standards, USP 797 sterility and batch testing.
  • No payment taken unless a provider approves you.

Where it wins: Genuinely no subscription — you buy a block and nothing recurs. Watch for: The $133 is the starter protocol. Moving to the high-dose protocol takes it to $183/month, and both are prepaid three-month commitments.

What each programme publishes: Noom Med

  • Noom Med listed from $149/month.
  • Microdose GLP-1Rx programme listed from $79/month with medication included.
  • Programme pairs low-dose medication with biomarker monitoring and coaching.

Where it wins: The coaching is the actual product here and it is well built. Watch for: A $79 microdose programme is not the same treatment as 10 mg tirzepatide. Check the dose before comparing on price.

Strengths of each

Fifty 410.

  • Genuinely no subscription — you buy a block and nothing recurs.
  • Among the lowest tirzepatide rates verified.
  • Unusually detailed public explanation of 503A standards and batch testing.

Noom Med.

  • The coaching is the actual product here and it is well built.
  • Medication is included in the microdose tier rather than billed separately.
  • Straightforward cancellation.

How they score

What we weighWeightFifty 410Noom
True monthly cost30%4.83.6
Price honesty20%4.63.2
Clinical support20%3.53.8
Pharmacy sourcing15%4.23.3
Cancelling15%3.33.6

Fifty 410 scores higher overall at 4.2 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.

Which suits you

  • Pick Fifty 410 if cost is the binding constraint. Over a year the gap is about $192, which is real money for the same class of medication.
  • Pick Noom Med if what it does better matters to you — the coaching is the actual product here and it is well built.
  • Ask both which pharmacy compounds the medication and whether it is a 503A or 503B facility. Neither publishes it.

The verdict

For most people starting out, Fifty 410 at $133 a month is the more defensible choice on arithmetic alone. Noom Med earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: Fifty 410 and Noom Med.

How they sit against everyone else

ProgrammePer monthDose-priceOur score
Coreage Rx
Best overall on true monthly cost
$199Flat4.5
Trimi
Lowest flat price with named pharmacies
$125Varies4.6
PlexusDx
Pharmacy transparency and genetic testing
$189Varies4.4
Ozari Health
Lowest advertised semaglutide price
$125Varies4.4
Fifty 410
Prepaid blocks with no subscription
$133Varies4.2
Ivím Health
Unlimited clinician access
$199Varies4
Mochi Health
Insurance concierge support
$278
incl. $79 fee
Varies3.6
Coby Health
Multi-month value with supplies included
$239Varies3.6
Hims & Hers
Widest range of formats
$238
incl. $39 fee
Varies3.5
Ro
Branded medication with insurance help
$448
incl. $149 fee
Varies3.5
Zealthy
Low-cost entry with insurance routing
$216Varies3.5
LifeMD
Insurance coordination
$149Varies3.5

Read next

  • Fifty 410 tirzepatide review

    Prepaid blocks with no subscription. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $133 a month.

  • Noom Med tirzepatide review

    Behaviour change alongside medication. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $149 a month.

  • How to spot a bad seller

    The FDA sent more than 55 warning letters to online GLP-1 sellers in one day. Here is how to tell a licensed programme from the rest.

  • The twelve-month cost

    Month one is the cheapest month you will have. Here is the full-year arithmetic, including the costs nobody puts in the advert.

  • Best programmes if this is your first time

    Ranked on how they price the dose ladder and how reachable support is — the two things that decide whether a beginner stays on treatment.