TrimRx vs Henry Meds
$399/mo against $449/mo for tirzepatide. Which is worth it, and for whom.
Updated 2026-09-18
How we are paid: one company on this page — Coreage Rx — pays us a commission if you sign up through our link. It does not buy a better score, a higher position, or the removal of a single criticism. Our rating method and full disclosure are both public.
Both sell tirzepatide. TrimRx costs $399 a month and Henry Meds costs $449, a difference of $50 a month or about $600 a year. The other differences matter more than the money if this is your first course.
TrimRx is all-inclusive compounded pricing. Henry Meds is sublingual and oral formats. They are not aimed at the same person, and the cheaper one is not automatically the right answer — particularly if this is your first course and you expect a slow titration.
Side by side
| TrimRx | Henry Meds | |
|---|---|---|
| Advertised from | $349 | $399 |
| Membership on top | None | None |
| True monthly cost | $399 | $449 |
| Roughly, per year | $4,788 | $5,388 |
| Price includes medication | Yes | Yes |
| Names its pharmacy | Not published | Not published |
| Our score | 2.9 / 5 | 3 / 5 |
Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.
The differences that affect treatment
They differ on 1 of the 7 things we track, and behave the same on the other 6. The differences are what the price gap is actually buying.
| TrimRx | Henry Meds | |
|---|---|---|
| Offers an oral or sublingual option | No | Yes |
What each programme publishes: TrimRx
- Compounded tirzepatide advertised at $349/month.
- Checkout has been reported billing $399/month on ongoing month-to-month terms.
- Pricing is described as all-inclusive of consultation, medication and supplies.
Where it wins: One price covers consultation, medication and supplies. Watch for: Read the ongoing rate on the checkout screen, not the landing page. Reported billing is $399/month.
What each programme publishes: Henry Meds
- Injectable tirzepatide listed at $399 for the first month and $449/month recurring.
- Oral tirzepatide tablets listed at $299 first month, $349/month recurring.
- Compounded semaglutide injection around $297/month; sublingual around $249/month with a $179/month tier.
- Three-month oral tirzepatide supply $1,047, or $891 paid in full.
- Three-month oral semaglutide supply $747, or $537 paid in full.
- Advertising states pricing "starts at $179/month", which corresponds to the lowest sublingual tier.
Where it wins: No membership fee layered on top of medication. Watch for: The advertised "starts at $179" is the sublingual tier. Weekly injectable tirzepatide renews at $449/month.
Strengths of each
TrimRx.
- One price covers consultation, medication and supplies.
- No separate membership fee.
Henry Meds.
- No membership fee layered on top of medication.
- Real choice of sublingual, oral tablet and injection.
- Discounts for paying a multi-month block up front.
How they score
| What we weigh | Weight | TrimRx | Henry Meds |
|---|---|---|---|
| True monthly cost | 30% | 2.5 | 2.3 |
| Price honesty | 20% | 2.4 | 2.8 |
| Clinical support | 20% | 3.4 | 3.7 |
| Pharmacy sourcing | 15% | 3.3 | 3.6 |
| Cancelling | 15% | 3 | 2.9 |
Henry Meds scores higher overall at 3 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.
Which suits you
- Pick TrimRx if cost is the binding constraint. Over a year the gap is about $600, which is real money for the same class of medication.
- Pick Henry Meds if what it does better matters to you — no membership fee layered on top of medication.
- Ask both which pharmacy compounds the medication and whether it is a 503A or 503B facility. Neither publishes it.
The verdict
For most people starting out, TrimRx at $399 a month is the more defensible choice on arithmetic alone. Henry Meds earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: TrimRx and Henry Meds.
How they sit against everyone else
| Programme | Per month | Dose-price | Our score |
|---|---|---|---|
| Coreage Rx Best overall on true monthly cost | $199 | Flat | 4.5 |
| Trimi Lowest flat price with named pharmacies | $125 | Varies | 4.6 |
| PlexusDx Pharmacy transparency and genetic testing | $189 | Varies | 4.4 |
| Ozari Health Lowest advertised semaglutide price | $125 | Varies | 4.4 |
| Fifty 410 Prepaid blocks with no subscription | $133 | Varies | 4.2 |
| Ivím Health Unlimited clinician access | $199 | Varies | 4 |
| Mochi Health Insurance concierge support | $278 incl. $79 fee | Varies | 3.6 |
| Coby Health Multi-month value with supplies included | $239 | Varies | 3.6 |
| Hims & Hers Widest range of formats | $238 incl. $39 fee | Varies | 3.5 |
| Ro Branded medication with insurance help | $448 incl. $149 fee | Varies | 3.5 |
| Zealthy Low-cost entry with insurance routing | $216 | Varies | 3.5 |
| LifeMD Insurance coordination | $149 | Varies | 3.5 |
Read next
- TrimRx tirzepatide review
All-inclusive compounded pricing. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $399 a month.
- Henry Meds tirzepatide review
Sublingual and oral formats. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $449 a month.
- How to spot a bad seller
The FDA sent more than 55 warning letters to online GLP-1 sellers in one day. Here is how to tell a licensed programme from the rest.
- The twelve-month cost
Month one is the cheapest month you will have. Here is the full-year arithmetic, including the costs nobody puts in the advert.
- Best programmes if this is your first time
Ranked on how they price the dose ladder and how reachable support is — the two things that decide whether a beginner stays on treatment.