Using the shot

Ozari Health vs PlexusDx

$125/mo against $189/mo for tirzepatide. Which is worth it, and for whom.

Illustration of two objects on a balance scale

Updated 2026-09-18


Both sell tirzepatide. Ozari Health costs $125 a month and PlexusDx costs $189, a difference of $64 a month or about $768 a year. The other differences matter more than the money if this is your first course.

Ozari Health is lowest advertised semaglutide price. PlexusDx is pharmacy transparency and genetic testing. They are not aimed at the same person, and the cheaper one is not automatically the right answer — particularly if this is your first course and you expect a slow titration.

What this means for your titration. PlexusDx holds one price at every dose and Ozari Health does not — so this gap widens as you titrate toward a therapeutic dose, exactly when you can least afford a surprise.

Side by side

OzariPlexusDx
Price at your starting dose$125$189
Price at your highest doseMay be higher — ask$189
Can you hold a dose for free?Check firstYes
Month-to-month availableYesYes

Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.

The differences that affect treatment

3 of these affect how treatment actually goes. The rest are administrative.

OzariPlexusDx
Price is the same at every doseNoYes
Names the compounding pharmacy publiclyNoYes
Offers an oral or sublingual optionNoYes

What each programme publishes: Ozari Health

  • Compounded semaglutide advertised from $86/month — the lowest verified rate in this comparison.
  • Physician review through Arora Health, the same clinical network behind Trimi, with named medical directors.
  • States on its own pages that compounded medications are not FDA-approved.

Where it wins: The lowest advertised compounded semaglutide price we have verified. Watch for: Confirm whether $86 is a month-to-month rate or requires a longer commitment, and ask which pharmacy compounds it.

What each programme publishes: PlexusDx

  • GLP-1 weight-loss programmes start at $129/month.
  • Publicly names six 503A pharmacy partners: Belmar, Strive, Epiq Scripts, Casa Pharma Rx, The Pharmacy Hub and Foothills.
  • Clinical oversight via LionMD, with named physicians and NPI numbers published.

Where it wins: The most detailed pharmacy disclosure in this comparison — six named 503A partners. Watch for: The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier.

Strengths of each

Ozari Health.

  • The lowest advertised compounded semaglutide price we have verified.
  • No membership fee and free expedited shipping included.
  • Names its physician network and medical directors.

PlexusDx.

  • The most detailed pharmacy disclosure in this comparison — six named 503A partners.
  • Names its prescribing physicians along with their NPI numbers.
  • No membership fee, and flat pricing across the dose range.

Ozari Health scores higher overall at 4.4 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.

Which suits you

If this is your first course, weight the two rows about dose pricing above everything else. A programme that keeps the price flat lets you stop climbing when your body says so, and that single freedom does more for whether you are still taking this in month three than $64 a month does.

The verdict

For most people starting out, Ozari Health at $125 a month is the more defensible choice on arithmetic alone. PlexusDx earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: Ozari Health and PlexusDx.

How they sit against everyone else

ProgrammePer monthDose-priceOur score
Coreage Rx
Best overall on true monthly cost
$199Flat4.5
SuperHealthy Rx
Public offer; not independently scored
$135VariesNot scored
Likeness Rx
Public offer; not independently scored
$199VariesNot scored
Trimi
Lowest flat price with named pharmacies
$125Varies4.6
PlexusDx
Pharmacy transparency and genetic testing
$189Varies4.4
Ozari Health
Lowest advertised semaglutide price
$125Varies4.4

Read next

  • Ozari Health tirzepatide review

    Lowest advertised semaglutide price. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $125 a month.

  • PlexusDx tirzepatide review

    Pharmacy transparency and genetic testing. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $189 a month.

  • How to spot a bad seller

    The FDA sent more than 55 warning letters to online GLP-1 sellers in one day. Here is how to tell a licensed programme from the rest.

  • The twelve-month cost

    Build a year-long budget from actual charges, supply periods and the terms for stopping future payments.

  • Best programmes if this is your first time

    Ranked on how they price the dose ladder and how reachable support is — the two things that decide whether a beginner stays on treatment.

Coreage Rx pays us a commission on sign-ups through our links. It does not affect our scores or rankings. How we rate · Disclosure