Using the shot

Hims & Hers vs TrimRx

$238/mo against $399/mo for tirzepatide. Which is worth it, and for whom.

Illustration of two objects on a balance scale

Updated 2026-09-18


Both sell tirzepatide. Hims & Hers costs $238 a month and TrimRx costs $399, a difference of $161 a month or about $1,932 a year. The other differences matter more than the money if this is your first course.

Hims & Hers is widest range of formats. TrimRx is all-inclusive compounded pricing. They are not aimed at the same person, and the cheaper one is not automatically the right answer — particularly if this is your first course and you expect a slow titration.

What this means for your titration. Both price the same way as your dose climbs, so the gap between them stays constant the whole way up the ladder.

Side by side

Hims & HersTrimRx
Price at your starting dose$238$399
Price at your highest doseMay be higher — askMay be higher — ask
Can you hold a dose for free?Check firstCheck first
Month-to-month availableYesYes

Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.

The differences that affect treatment

2 of these affect how treatment actually goes. The rest are administrative.

Hims & HersTrimRx
Offers an oral or sublingual optionYesNo
Can dispense FDA-approved branded medicationYesNo

What each programme publishes: Hims & Hers

  • Weight-loss membership advertised at $39 for the first month.
  • Company has announced oral semaglutide pricing starting around $49/month, with the 1.5 mg dose around $149/month.

Where it wins: One account covers oral, compounded injectable and branded options. Watch for: The advertised entry prices and the membership are separate charges. Add $39/month to whatever medication figure you were quoted.

What each programme publishes: TrimRx

  • Compounded tirzepatide advertised at $349/month.

Where it wins: One price covers consultation, medication and supplies. Watch for: Read the ongoing rate on the checkout screen, not the landing page. Reported billing is $399/month.

Strengths of each

Hims & Hers.

  • One account covers oral, compounded injectable and branded options.
  • Large enough to keep supply steady when smaller sellers run dry.
  • Branded Zepbound is available without leaving the platform.

TrimRx.

  • One price covers consultation, medication and supplies.
  • No separate membership fee.

Hims & Hers scores higher overall at 3.5 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.

Which suits you

If this is your first course, weight the two rows about dose pricing above everything else. A programme that keeps the price flat lets you stop climbing when your body says so, and that single freedom does more for whether you are still taking this in month three than $161 a month does.

The verdict

For most people starting out, Hims & Hers at $238 a month is the more defensible choice on arithmetic alone. TrimRx earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: Hims & Hers and TrimRx.

How they sit against everyone else

ProgrammePer monthDose-priceOur score
Coreage Rx
Best overall on true monthly cost
$199Flat4.5
SuperHealthy Rx
Public offer; not independently scored
$135VariesNot scored
Likeness Rx
Public offer; not independently scored
$199VariesNot scored
Trimi
Lowest flat price with named pharmacies
$125Varies4.6
PlexusDx
Pharmacy transparency and genetic testing
$189Varies4.4
Ozari Health
Lowest advertised semaglutide price
$125Varies4.4

Read next

  • Hims & Hers tirzepatide review

    Widest range of formats. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $238 a month.

  • TrimRx tirzepatide review

    All-inclusive compounded pricing. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $399 a month.

  • How to spot a bad seller

    The FDA sent more than 55 warning letters to online GLP-1 sellers in one day. Here is how to tell a licensed programme from the rest.

  • The twelve-month cost

    Build a year-long budget from actual charges, supply periods and the terms for stopping future payments.

  • Best programmes if this is your first time

    Ranked on how they price the dose ladder and how reachable support is — the two things that decide whether a beginner stays on treatment.

Coreage Rx pays us a commission on sign-ups through our links. It does not affect our scores or rankings. How we rate · Disclosure