Using the shot

Fifty 410 vs Eden

$133/mo against $298/mo for tirzepatide. Which is worth it, and for whom.

Illustration of two objects on a balance scale

Updated 2026-09-18


Both sell tirzepatide. Fifty 410 costs $133 a month and Eden costs $298, a difference of $165 a month or about $1,980 a year. The other differences matter more than the money if this is your first course.

Fifty 410 is prepaid blocks with no subscription. Eden is low advertised medication price. They are not aimed at the same person, and the cheaper one is not automatically the right answer — particularly if this is your first course and you expect a slow titration.

What this means for your titration. Eden holds one price at every dose and Fifty 410 does not — so this gap widens as you titrate toward a therapeutic dose, exactly when you can least afford a surprise.

Side by side

Fifty 410Eden
Price at your starting dose$133$298
Price at your highest doseMay be higher — ask$298
Can you hold a dose for free?Check firstYes
Month-to-month availableNo — prepaidYes

Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.

The differences that affect treatment

2 of these affect how treatment actually goes. The rest are administrative.

Fifty 410Eden
Price is the same at every doseNoYes
Month-to-month without prepaying a blockNoYes

What each programme publishes: Fifty 410

  • Compounded tirzepatide starter protocol at $133/month, sold as a $399 three-month block.
  • States it is a telehealth platform that does not compound or distribute medication itself, and that preparations come from FDA-registered 503A pharmacies.
  • Publishes unusually detailed information on 503A standards, USP 797 sterility and batch testing.

Where it wins: Genuinely no subscription — you buy a block and nothing recurs. Watch for: The $133 is the starter protocol. Moving to the high-dose protocol takes it to $183/month, and both are prepaid three-month commitments.

What each programme publishes: Eden

  • Compounded semaglutide advertised at $99/month.

Where it wins: Genuinely low medication-only pricing. Watch for: The $99 semaglutide headline becomes roughly $198/month once the membership renews at its ongoing rate.

Strengths of each

Fifty 410.

  • Genuinely no subscription — you buy a block and nothing recurs.
  • Among the lowest tirzepatide rates verified.
  • Unusually detailed public explanation of 503A standards and batch testing.

Eden.

  • Genuinely low medication-only pricing.
  • Fast onboarding with flat rates across published dose ranges.

Fifty 410 scores higher overall at 4.2 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.

Which suits you

If this is your first course, weight the two rows about dose pricing above everything else. A programme that keeps the price flat lets you stop climbing when your body says so, and that single freedom does more for whether you are still taking this in month three than $165 a month does.

The verdict

For most people starting out, Fifty 410 at $133 a month is the more defensible choice on arithmetic alone. Eden earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: Fifty 410 and Eden.

How they sit against everyone else

ProgrammePer monthDose-priceOur score
Coreage Rx
Best overall on true monthly cost
$199Flat4.5
SuperHealthy Rx
Public offer; not independently scored
$135VariesNot scored
Likeness Rx
Public offer; not independently scored
$199VariesNot scored
Trimi
Lowest flat price with named pharmacies
$125Varies4.6
PlexusDx
Pharmacy transparency and genetic testing
$189Varies4.4
Ozari Health
Lowest advertised semaglutide price
$125Varies4.4

Read next

  • Fifty 410 tirzepatide review

    Prepaid blocks with no subscription. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $133 a month.

  • Eden tirzepatide review

    Low advertised medication price. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $298 a month.

  • How to spot a bad seller

    The FDA sent more than 55 warning letters to online GLP-1 sellers in one day. Here is how to tell a licensed programme from the rest.

  • The twelve-month cost

    Build a year-long budget from actual charges, supply periods and the terms for stopping future payments.

  • Best programmes if this is your first time

    Ranked on how they price the dose ladder and how reachable support is — the two things that decide whether a beginner stays on treatment.

Coreage Rx pays us a commission on sign-ups through our links. It does not affect our scores or rankings. How we rate · Disclosure